Dealing with LOCK through OTA script

Hello,

In my use case, a perl script udpates the Test Instance fields based on a trigger from bugzilla. Now, the problem is.. When someone is accessing any run associated with that instance ( through UI ), the script is failing (silently) to update it. I dont know what will be the ideal solution for this. Has anybody came around this before ?

1) Can i unlock the RUN and INSTANCE and push the udpates ?

2) Can i prompt the user to close the window as the script is trying to make a change ?

3) Can i wait till the lock is released.. ?

I didnt try any of these.. just want to know other's opinions.